Friday, July 17, 2015

Deadly intestinal disease by eNose smelled at incubator babies – National Care Guide

A device can in premature children the serious disease necrotizing enterocolitis (NEC) detection at an early stage. According to research conducted by VUmc. This eNose (an electronic ‘nose’) can predict from the smell of feces that the disease develops within days. This gives physicians the long term possibility to intervene in previously, so as to increase the chance of survival. This reports the VU University Medical Center.

Children who are born prematurely are vulnerable. In about 10 percent of very preterm babies (gestation less than 28 weeks), the disease for NEC. This is a serious inflammation of the intestine as a result of immaturity by premature birth, to which dies to 30 percent of the patients. But the children who survive often suffer lifelong serious consequences as developmental and dependence on food via the bloodstream.

NEC is currently only recognized when the baby is already very ill ; this is very unfavorable for the prognosis. It VUmc researchers are now trying to end. They have in a group of prematurely born children during the first four weeks of life with the aid of a eNose the smell of the feces analyzed from the diapers. The researchers examined a group of 128 premature babies who were treated at VU University Medical Center, AMC and the Maxima Medical Centre (Veldhoven). Of the children developed, 13 disease NEC, 7 of whom are deceased within 24 hours.

The investigation showed that the odor profiles of the children who were later NEC, already three days in advance significantly different from healthy controls. The day prior to the diagnosis of NEC eNose could discern the NEC group. “These low-impact and low-odor analysis has great potential as a future predictor of NEC,” says project manager Tim de Meij, pediatrician MDL at VU University Medical Center. He and gastroenterologist Nanne de Boer the inventor of the use of the eNose to recognize various intestinal diseases in children and adults.

© National Care Guide

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